ABSTRACT
I. Introduction ........................................................................................................................ 1436 II.N-Oxidation ....................................................................................................................... 1436
A.Alkaloids .................................................................................................................... 1436 1.Levobupivacaine .................................................................................................. 1436 2.Tetrahydroisoquinoline Alkaloids ....................................................................... 1437
III. Coupling of Electron-Rich Aromatics ............................................................................... 1438 A.O-Methylthalibrine ..................................................................................................... 1438
IV.Electrogenerated Reagents ................................................................................................. 1439 A.Hypervalent Iodine ..................................................................................................... 1439
1.Tetrahydropyrroloiminoquinone alkaloids .......................................................... 1439 B. Methoxy Radical ........................................................................................................ 1439
1.En Route to Parasitenone ..................................................................................... 1439 V.Umpolung ........................................................................................................................... 1441
A.Bicyclo [3.2.1] Skeleton .............................................................................................. 1441 B.(−)-Crobarbatic Acid, (+)-Nemorensic Acid ............................................................... 1441
VI. Terpenoids .......................................................................................................................... 1443 A.Furan-Olešn Coupling ............................................................................................... 1443
1.Eunicellin Diterpenes .......................................................................................... 1443 2.Cyathin Core........................................................................................................ 1443 3.Tricholomalide A ................................................................................................. 1444 4. (−)-Alliacol A ...................................................................................................... 1446 5.Arteannuin Skeleton ............................................................................................ 1448 6.(−)-Heptemerone B and (−)-Guanacastepene E ................................................... 1449
VII.Mediators ........................................................................................................................... 1450 A.Daucene ...................................................................................................................... 1450
VIII. Oxidative Dearomatization .................................................................................................1451 A.Introductory Remarks .................................................................................................1451 B.Heliannuol E ............................................................................................................... 1453
IX.Cycloaddition Reactions .................................................................................................... 1454 A.Quinone Methides ...................................................................................................... 1454
1. Euglobals ............................................................................................................. 1454 B.Azaquinones ............................................................................................................... 1454
1.Neuroprotective Agents ....................................................................................... 1454
The tremendous structural diversity of natural products, coupled with their intriguing and oftentimesusefulbioactivities,continuestointerestandstimulatethecreativityofchemists.Wenote thattheroleofelectrochemistryinthedesignandsynthesisofthesematerialsisincreasing,justas thenumberofpersonswhorealizetheimportanceandutilityofelectrochemicaltoolsisincreasing. Itseemsclearthattheimportantadvancesthatcontinuetobemadebyelectrochemistsareopening the eyes of traditional organic chemists who have previously not embraced the šeld [1-7]. They havebeguntomorefullyappreciatethatredoxchemistryprovidesmanyimportanttoolsthatcanbe usedtomakenewbondsandconstructcomplexframeworks,andthatitismuchmorethansimplya meanstooxidizeanalcoholorreduceacarbonylunit.Agreaterappreciationforthefactthatmany electrochemicalprocessesaccordwiththetenantsofgreenchemistryandprovidemethodsthat contribute to sustainability is also important [8,9].
