ABSTRACT

Which of the following studies would be most likely to aid diagnosis of an underlying condition to account for her disease?

a. Sensitive thyroid-stimulating hormone b. Skin biopsy c. CT of chest, abdomen, and pelvis d. MRI of proximal muscles in legs e. Muscle biopsy

21. A 36-year-old man has a several-month history of dry eyes and mouth and parotid gland swelling. He has no joint symptoms

Hemoglobin 11.1 g/dL Leukocytes 6.4 × 109/L Sedimentation rate 62 mm in 1 hour Antinuclear antibody titer 1:160 Creatine kinase 4,210 U/L (normal <200) Electromyography Inflammatory myopathy

included negative results of antinuclear antibody, anti-Sjögren syndrome A (SSA), and rheumatoid factor tests. Which of the following is the most likely cause of his parotid swelling and sicca syndromes?