ABSTRACT

The term goal-oriented therapy describes a relatively new therapeutic concept in the field of pulmonary arterial hypertension (PAH), which focuses on the question when a response to therapy can be considered sufficient and when not. This question is of fundamental importance in guiding therapeutic decisions, that is, when to maintain a therapy, when to switch from one medication to another, and when to combine several medications. The goal of modern PAH therapy is not simply to achieve a certain degree of clinical improvement but to achieve disease control, which means to ascertain an acceptable clinical status and to keep the patient stable for as long as possible.