ABSTRACT
Over the past 20 years, the use of assisted reproductive technologies has changed the choices available for older women. These choices include donor egg in vitro fertilization (DE IVF), which is now a standard treatment in most IVF centers. Patients who might benefit from DE IVF include women with premature ovarian failure, ovarian failure due to either chemotherapy or radiation, and women with gonadal dysgenesis.A second and much larger group includes women with diminished ovarian function, and today, the predominant indication for egg donation at most IVF centers is diminished ovarian reserve in women with functioning ovaries. Other candidates include women who have previously failed multiple IVF attempts and women carrying transmittable genetic abnormalities that could affect their offspring.
