ABSTRACT

The term “bioactive food” was rst de ned “as foods, food ingredients, or dietary supplements that demonstrate speci c health or medical bene ts including the cancer prevention and treatment of disease beyond basic nutritional functions” (Baichwal, 1999, pp. 19-20). Now bioactive foods

Introduction .................................................................................................................................... 143 Time Series of Awareness in Bioactive Foods ............................................................................... 144

What are Bioactive Foods? ................................................................................................... 145 How Bioactive Foods Act? ................................................................................................... 145 Evidences of Bioactive Foods as being Anticancer .............................................................. 153

Anticancer Properties of Bioactive Foods and Herbs .................................................................... 154 Nutrition Requirement of Anticancer Herb Active Components in Human Use

Approved by U.S. Food and Drug Administration ................................................... 155 Biochemical Mechanisms of Tumor Treatment by Nutraceuticals from Bioactive Foods ... 155 Biochemical Basis of Anticancer Activity of Bioactive Foods ............................................. 156

Concepts on Biochemical Role of Cytochromes in Cancer Prevention ................... 159 Dietary Chemicals as Modulators of Carcinogen Metabolism ................................. 160 Isothiocyanates in Bioactive Foods as Example ....................................................... 162 Inhibition of the Cytochrome P450-mediated Bioactivation of Chemical

Carcinogens by Isothiocyanates ................................................................. 162 Detoxication of Reactive Intermediates: Glutathione Transferase and

Quinine Reductase Chemopreventive Activity .......................................... 163 Pharmaceutical Approach of Herbal Formula with Anticancer Properties ........................... 163 Alternative Approaches of Bioactive Foods in Cancer Prevention Formulation .................. 164

Present State of Art on Bioactive Foods in Cancer Prevention ...................................................... 165 Insurance and Prescription .................................................................................................... 165 Criteria of Nutrition Supplement Practice of Bioactive Foods in Cancer

Prevention: A Government Policy ............................................................................ 165 Recent Advances on Bioactive Foods in Cancer .................................................................. 166

Bioactive Foods in Cancer Prevention: A Quick Survey 2000-2009 ............................................ 166 Mechanism of Cancer Prevention by Herbs ......................................................................... 166 Cancers in the Human Body and Bioactive Foods ............................................................... 168 Challenges, Hypes, Hopes and Futuristic Role of Bioactive Foods ..................................... 170

Conclusion ..................................................................................................................................... 170 Acknowledgments .......................................................................................................................... 171 References ...................................................................................................................................... 171

have emerged as potential supplements in cardiovascular and cancer preventive natural sources from food (Baichwal, 1999; Amin et al., 2009).