ABSTRACT
Psoriatic arthritis (PsA) is a chronic, seronegative in–ammatory arthritis that is often associated with psoriasis. It is a heterogeneous disease with varied presentation. On the basis of clinical and immunohistopathological characteristics and HLA associations, PsA is classi—ed as a spondyloarthropathy [1-3]. Clinical manifestations are diverse and range from dactylitis, enthesitis, monoarthritis, oligoarthritis, symmetric polyarthritis, distal interphalangeal (DIP) predominant arthritis, sacroiliitis, spondylitis, and arthritis mutilans. The clinical manifestations can occur in combination. Early in PsA, the disease is usually oligoarticular and mild; over time, it can evolve into a polyarticular disease with increased severity [1].
