ABSTRACT

Nonsteroidal anti-in–ammatory drugs (NSAIDs) are one of the most commonly prescribed medicines worldwide. In the United States, it is estimated that more than 70 million prescriptions and more than 30 billion over-the-counter tablets of these drugs are sold annually [1]. At lower over-thecounter doses, these drugs are used to treat pain. When given at higher doses, these medicines may also be helpful in reducing in–ammation.