ABSTRACT
Arthritis is a broad term used to describe encompassing more than 100 chronic and debilitating diseases of the joints, bones, and muscles [1, 2]. The two most common types are rheumatoid arthritis (RA) and osteoarthritis (OA). RA is a chronic in–ammatory disease that is characterized by the attack of killer T cells on type II joint collagen, resulting in damage to cartilage with manifestations of joint swelling, pain, and in–ammation and further into the deformity and destruction of joints
Introduction .................................................................................................................................... 385 Plant Seed Oils ............................................................................................................................... 386
History of Plant Seed Oils .................................................................................................... 386 Production Methodology ...................................................................................................... 386 Compositions of Plant Oils ................................................................................................... 387
FAs and Metabolism ...................................................................................................................... 387 Classi—cations of FAs ........................................................................................................... 387 Ingested FAs ......................................................................................................................... 389 FAs and Eicosanoids ............................................................................................................. 389
PUFA-Derived Eicosanoids in RA ................................................................................................. 389 Different Eicosanoids ........................................................................................................... 389 RA-linked Eicosanoids ......................................................................................................... 389 PUFA and Eicosanoids .........................................................................................................390
PUFAs and In–ammatory Diseases: RA ........................................................................................ 391 α -Linolenic Acid .................................................................................................................. 391
