ABSTRACT

High resolution in vivo peripheral quantitative computed tomography (HR-pQCT) provides detailed information on bone structure (see Figure 15.1). In particular, bone is readily modeled by a direct mapping of HR-pQCT voxels to bone elements. Obviously, bone density estimates are easily computed from this voxel model. In fact, the analysis of bone density is today’s standard approach of predicting bone strength and fracture risk in diseases like osteoporosis, that is, according to the World Health Organization (WHO), second only to cardiovascular disease as a leading health care problem.