Chapter 3Coarse-Grained Modeling of Large Protein Complexes for Understanding Their Conformational Dynamics

Conformational Transitions ................................................................ 74 3.5 De Novo Elastic Network Models ..................................................................77

3.5.1Elastic Network Models Established from Molecular Simulations ........................................................................77 3.5.2Coarse-Grained Elastic Network Models ........................................... 78 3.5.3 Multiscale Elastic Network Model .....................................................80