ABSTRACT
Treatment of overweight and obesity is exceedingly difcult. Conventional management consists of low-calorie diets, physical activity, behavioral interventions, and/or pharmacological agents. However, long-term adherence to these approaches is problematic and most individuals regain the majority of lost weight within 1 or 2 years.1 It has been suggested that the addition of novel approaches to conventional treatments may produce sustainable weight loss. One approach is ber supplements. Glucomannan, a water-soluble dietary ber supplement, has been associated with reductions in body weight in a few small studies2-7 and may be an effective adjunct for overweight and obese individuals.
