ABSTRACT
Optical coherence tomography (OCT) is a high-resolution optical imaging modality that was invented around 1990 [1-3] and rapidly developed as a diagnostic imaging tool for retinal diseases. Its rapid development can be attributed at least in part to the fact that no other imaging modality was able to produce high-resolution cross-sectional images through the entire thickness of the retina without making contact with the eye. Carl Ziess Meditec introduced the rst commercial OCT system for retinal imaging in 1995. Since then, commercial instruments for clinical imaging have been introduced for the anterior segment of the eye and more recently for intravascular imaging of the coronary arteries. In the last 10 years, a number of small-and medium-sized companies have brought to market research-grade OCT systems intended for use in biomedical and related elds. e eld has matured to the point where incorporating OCT imaging as part of a research plan is as easy as incorporating some of the more classic optical imaging modalities like uorescence microscopy.
