ABSTRACT

Hyperglycaemia in the antenatal period can have a major impact on foetal beta cell and adipocyte development1 and can lead to neonatal hypoglycaemia, macrosomia, polycythaemia, hyperbilirubinaemia, and hypomagnesaemia.2 There is growing evidence that exposure to hyperglycaemia in utero may increase the risk of future obesity and diabetes in the offspring.3-5 The relationship between maternal hyperglycaemia and adverse maternal/neonatal adverse outcomes is continuous with no threshold.6