ABSTRACT

Garlic (Allium sativum) holds a unique position in history and was recognized for its nutritional and therapeutic potential. Garlic is also an important component in herbal medicine. Traditionally, it has been employed to treat infections, wounds, diarrhea, rheumatism, heart disease, diabetes, and many other disorders. Experimentally, it has been shown to exert antilipidemic, antihypertensive, antineoplastic, antibacterial, immunostimulant, and hypoglycemic actions. Clinically, garlic has been evaluated for a number of conditions, including hypertension, hypercholesterolemia, intermittent claudication, diabetes, rheumatoid arthritis, common cold, and for the prevention of arteriosclerosis and cancer. However, the experimental and clinical evidences are more favorable for the application of garlic against cardiovascular disorder. Most research articles published during

20.1 Introduction .......................................................................................................................... 387 20.2 Hyperlipidemia Effect .......................................................................................................... 388

20.2.1 Animal Study ............................................................................................................ 389 20.2.2 Human Study ............................................................................................................ 389 20.2.3 Facts from Artifacts ..................................................................................................390