ABSTRACT

Introduction 422

Pathology and classification of DTC 423

The thyroid nodule 424

Molecular genetics of thyroid cancer 429

Treatment of DTC 431

Surgical treatment of DTC 432

Surgical management of the thyroid gland in papillary

thyroid cancer 434

Surgical management of the thyroid in FTC 434

Surgical management of the neck in DTC 434

Management of extrathyroid extension 435

Management of differentiated thyroid cancer in pregnancy 435

Management of DTC in childhood 436

Adjuvant therapies 436

Follow up 436

Thyroglobulin levels 437

Radiological imaging studies in patients with elevated

serum Tg levels 437

Surgical management of recurrent DTC 438

Surgical anatomy 438

Surgical technique in DTC 440

Complications and outcome measurements 444

Conclusion 446

Directions for future research 446

Key evidence 447

Key learning points 447

References 448

There are in fact two things, science and opinion. The former begets knowledge, the latter ignorance.