ABSTRACT

Introduction 528

Anatomy of the pituitary gland 528

Physiology of the pituitary gland 529

Classification of pituitary tumours 530

Tumour size 530

Histology 530

Other lesions arising in and adjacent to the pituitary 531

Epidemiology and incidence 531

Clinical presentation of pituitary lesions 531

Investigations 531

Non-functioning adenoma 532

Functioning adenomas 533

Hypophysectomy 536

Patient information and consent 536

Preoperative investigations 537

Surgical approaches 537

Postoperative management 539

Discharge from hospital 540

Complications of surgery 540

Surgical outcomes 541

Role of radiotherapy in pituitary adenomas 541

The future for the surgical management of pituitary

tumours 542

Key evidence 542

Key learning points 542

References 542

Here in this well-concealed spot, almost to be covered by a thumb nail, lies the very mainspring of primitive existence – vegetative, emotional, reproductive – on which, with more or less success, man has come to superimpose a cortex of inhibitions.