ABSTRACT
Medical descriptions of right lower quadrant peritonitis, perityphlitis, appeared more than 500 years ago. Inflammation of the appendix was conclusively demonstrated to cause this condition by Reginald Fitz in 1886. The first published report on appendectomy is attributed to Claudius Amyand from England who, in 1736, removed an inflamed perforated and fistulizing appendix from the scrotum of an 11-year-old boy. The first deliberate appendectomy for perforated appendix was performed by Morton in 1887.
