ABSTRACT

Neuroblastoma is the most common abdominal malignancy of childhood, the annual incidence being about six cases per million children. These tumors arise in primitive precursors of the sympathetic nervous system and consequently are seen in the adrenal medulla and sites of sympathetic ganglia. Almost one-third are detected in the first 12 months of life and a further 50 percent between the ages of one and four years. Only 5 percent occur in children over the age of ten years.