ABSTRACT

Breast cancer is the most common cancer affecting women throughout the world (Bryle et al., 2003).It accounts highest morbidity and mortality worldwide. Globally, 1.9 million new cases of breast cancer were diagnosed and 0.6 million deaths were caused in the year 2009 from this disease (DeSantis et al., 2009, 2010). In India, breast cancer is the second most common cancer, where 0.07 million new cases and 0.035 million deaths are reported every year (Ghumare and Cunningham, 2007). The present trend in the management of cancer development involves either reduction of the exposure of an individual to known carcinogen to the extent possible or seeking advantage of the inhibitors of carcinogenesis for their eventual application as anticancer agents. Since, exposure to the environmental carcinogens is often unavoidable, the latter field has been widely explored.