ABSTRACT

Natural compounds have been used in traditional medicine for thousands of years, and a variety of evidence of their efciency has been accumulated. The role of the modern research is to reveal the relevance of those evidence for treatment and prevention of diseases and the ways of their integration with the conventional medicine. According to the Dietary Supplement, Health and Education Act, dietary

Natural Compounds in Modern Research .............................................................. 281 Microbiota .............................................................................................................. 282

Role of Microbiota in Etiology of Fatty Liver Disease ..................................... 282 Probiotic Supplementation in Fatty Liver Disease ............................................ 283 Role of Prebiotics in Fatty Liver Disease ..........................................................284

Methyl Donors: Choline, Betaine, and Folic Acid in Fatty Liver Disease.............286 Role of S-Adenosylmethionine in Liver Health and Disease ............................286 Role of Methyl Donors in Fatty Liver Disease .................................................287

Milk Thistle ............................................................................................................288 Green Tea ...............................................................................................................290 Nonclinical Evidence of a Role of Nutraceuticals in Prevention and Treatment of Fatty Liver Disease ............................................................................................292