ABSTRACT

Neurological diseases such as multiple sclerosis (MS) have a serious impact on the patient’s personal, professional, and social life. Progressive diseases such as Parkinson’s disease and multiple system atrophy will yield a different symptomatology than nonprogressive stabilizing disorders such as craniocerebral trauma, spinal cord injury, cauda equina syndrome. The prevalence of sexual disorders in women taking antidepressants varies from 22% to 58% with higher rates for selective serotonin reuptake inhibitors and lower rates for bupropion. The presence of other than sexual MS symptoms such as fatigue, spasticity, impaired coordination, impaired mobility, muscle weakness, bladder and bowel dysfunction, cognitive dysfunction, and medication side effects cause difficulty in experiencing sexual intercourse or other sexual acts. Many regions in the brain contribute to the sexual response, ranging from centers in the hindbrain to areas in the cerebral cortex.