ABSTRACT

Magnetic resonance imaging (MRI) was broadly introduced to the scientific community in 1973, when Paul C. Lauterbur published images representing the nuclear magnetic resonance (NMR) response of hydrogen nuclei in a pair of water-filled glass capillaries [1]. Onedimensional (1D) projections of this response were first obtained through a procedure that involved applying static magnetic field gradients to the sample, mapping NMR frequency onto the source position. A series of 1D projections, acquired along different gradient directions, were then combined to reconstruct a  two-dimensional (2D) image, as illustrated in Figure 1.1.