ABSTRACT
Gastric infections can cause two common conditions – gastritis and gastroenteritis. In 1983, Drs. Barry Marshall and Robin Warren successfully cultured the spiral organisms from human gastric antrum. Flagella and urease are very important for colonization of the gastric mucosa. The natural history and histologic findings of H. pylori gastritis in children differ from the adult population. Spontaneous clearing and reacquisition of the gastric infection in preschoolers has been reported in the literature. Most commonly H. pylori infection causes chronic active gastritis which is characterized by a striking infiltrate of the gastric epithelium and the underlying lamina propria by neutrophils, T and B lymphocytes, macrophages, and mast cells. Biopsy specimens from endoscopy stained with Giemsa stain usually demonstrate a variable number of H. pylori organisms adhering to the gastric epithelium, both coating the gastric wall and lining the gastric glands. Granulomatous gastritis is a rare disease characterized by the presence of granulomas within the gastric mucosa or submucosa.
