ABSTRACT
Mesothelioma, in common with other cancers, is caused by multiple somatic genetic alterations acquired during asbestos induced tumorigenesis. Knowledge of the common, underlying genetic features of mesothelioma may reveal new opportunities for enabling drug target discovery for personalized therapy as well as early diagnostics. is chapter aims to summarize current understanding of mesothelioma genetics, and in particular, to highlight current eorts to exploit common somatic genetic features for therapeutic benet.
