ABSTRACT
Traumatic brain injury (TBI) results from transduction of energy into the brain from an outside source. Approximately 1.4 million people sustain a TBI each year in the United States (Zohar et al. 2011), of which 40,000-50,000 die as a result of the injury. Traumatic brain injury has its greatest impact on young men and women, and it poses a tremendous burden to families and society in terms of years of lost productivity, increased demands on the health care system, and reduction in quality of life. It has been estimated that 5.3 million people in the United States are living with disabilities resulting from TBI, underscoring the necessity for proper diagnosis and intervention. Unfortunately, numerous therapies and treatments have failed in their ability to translate from basic science research to a clinically useful intervention.
