ABSTRACT
Lactobacillus plantarum is among the most prominent lactic acid bacterium (LAB), which has one of the largest genomes of LAB [1]. Due to this, it can express various genes that provide this species with a high ability to customized to varying external conditions, and also it can attach to different substrates [2]. Lb. plantarum has been isolated from a wide array of sources including fermented foods all over the world [3], and, many strains, have been proposed to confer benets on human health, being considered potential probiotics [4,5]. These human benets include treatment and prevention of enteric infections and post-antibiotic syndromes, acute infectious diarrhea, prevention of antibiotic-associated diarrhea, inammatory bowel disease (IBD), colorectal cancer (CRC), and treatment of irritable bowel syndrome. Lb. plantarum is also reported to be active against enteropathogens such as Listeria monocytogenes, L. innocuo, Staphylococcus aureus, and inuenza virus. Its benecial role in various diseases is discussed in detail in the following sections.
