ABSTRACT
Homogeneous pink color and dotted vessels uniformly distributed throughout the lesion. Reticular depigmentation, visible as a grid of whitish areas delineating pink areas representing the holes of the net, can be visualized in flat lesions. Spitz nevi (SN) are benign melanocytic proliferation characterized histologically by the presence of large and/or spindle-shaped melanocytes, usually arranged in nests. Most SN are predominantly compound, although junctional and intradermal lesions are also observed. Under dermoscopy, amelanotic SN present a homogeneous pink color, whereas a brownish hue, remnants of brown pigmentation, and tan/brown globules can be observed in hypopigmented lesions. Differential diagnosis of SN includes a series of nonmelanocytic lesions, such as juvenile xantho-granuloma, pyogenic granuloma, dermatofibroma, and viral wart. A conservative management have been proposed in children, based on the evidence that Spitz nevus is relatively common in children whereas melanoma is exceedingly rare.
