ABSTRACT
CONTENTS 17.1 Introduction 274 17.2 Fluence Map Optimization 275
17.2.1Model of the Problem 275 17.2.2GPU Implementation 276 17.2.3Experimental Results 278
17.3Direct Aperture Optimization 281 17.3.1Model of the Problem 281 17.3.2e Optimization Algorithm 282 17.3.3e Master Problem 282 17.3.4e Pricing Problem 282 17.3.5Experimental Results 285
17.4Conclusions and Discussions 287 References 289
Intensity-modulated radiation therapy (IMRT) is one of the most used techniques to treat many forms of cancer. In IMRT, the linear accelerator is equipped with a multileaf collimator (MLC) system. By dynamically moving the leaves, very complex dose distributions can be delivered to the patient; therefore, sucient dose can be delivered to the tumor, while nearby organs and tissues can be spared.
