ABSTRACT
I. A. NAGOVITSYN, G. K. CHUDINOVA, G. V. SIN’KO, G. A. PTITSYN, V. A. DANILOV, A. I. ZUBOV, V. V. KURILKIN, and G. G. KOMISSAROV
10.1 Aim and Background ..................................................................114 10.2 Introduction .................................................................................114 10.3 Experimental ...............................................................................116 10.4 Results and Discussion ...............................................................116 10.5 Conclusion ................................................................................. 124 Keywords .............................................................................................. 125 References ............................................................................................. 125
10.1 AIM AND BACKGROUND
Purpose-To determine the conditions for luminescence enhancement of 5,10,15,20-tetra (4-carbomethoxyphenyl) porphyrin Pd complex in the formation of inclusion complexes with b-cyclodextrin and serum albumin. Also the parameters of the complexes on the basis of quantum-mechanical calculations are being identified. Formation of inclusion complexes of insoluble porphyrins with serum albumins and cyclodextrins allows to obtain stable aqueous solutions for physicochemical studies, in which the photoactive compounds are screened from influence of aqueous medium, which leads to a considerable increase of their luminescence. A similar result is obtained by incorporation of porphyrins in micelles. Formation of such complexes is accompanied by changes in spectral characteristics, shear of absorption and luminescence bands, which depend on the structure of photoactive compound and the ratio of components in the complex. Selection of the preparation conditions of the complexes helps to achieve their optimal composition for specific basic research or practical applications. It is an important possibility in photosynthesis modeling-to use porphyrin compounds, more stable and cheap than natural pigments. Obtaining the inclusion complexes makes it possible to carry out physicochemical, photochemical, and biophysical research of photoactive molecules in dilute aqueous solutions of nanoscale complex materials.
