ABSTRACT
Apoptotic-cristae remodelling also causes the disorganization of respiratory chain SCs, resulting in an impairment of mitochondrial bioenergetics (Cogliati et al., 2013).
In order to satisfy the energetic requirement of cells, the OXPHOS is ne-tuned not only by modulation of cristae shape but also by a plethora of mechanisms such as post-translational modications, selective degradation by proteases and mitophagy.
