ABSTRACT

Air pollution is a serious global public health problem that has been linked to an increased risk of acute and chronic adverse human health conditions.12 Studies have shown that reductions in exposure at the population level significantly improve health outcomes.13,14 More specific to human reproductive technologies, numerous studies provide compelling evidence of the negative effects of poor air quality on embryo development, which ultimately affects pregnancy rates and outcomes.15-20 One such observation was made in Naples, Italy, in 1992, where an in vitro fertilization laboratory noted decreases in in vitro embryo development and pregnancy rates associated with the move from a suburban area to a more urban setting.