ABSTRACT

The increasing need for alternatives to fossil hydrocarbon-based chemicals and the recent advances in omics and metabolic engineering are promissory options for the development of biobased solutions for bioproducts and cell factories. Recent advances in omics in microalgae are now orientated toward the optimization and diversication of the production and applications of bioproducts. Moreover, omics approaches contribute to redene metabolism, functional diversity, and biosynthetic capacity of uxes of compounds of strains into a desired biosynthetic pathway (Guarnieri and Pienkos 2014). During the last couple of decades, microalgae have been considered as a suitable and valuable feedstock for biofuel, pharmaceuticals, nutraceutical, biomedical, and materials applications (Paniagua-Michel et al. 2014). Among the ubiquitous metabolites in microalgae, isoprenoids are one of the largest classes of small molecules found on earth with a wide variety of important functions and applications. Isoprenoids (also referred to as terpenes) constitute one of the most diverse groups of natural products in nature and derived from the universal precursors isopentenyl diphosphate (IPP) and its isomer, dimethylallyl

CONTENTS

3.1 Introduction .......................................................................................................................... 37 3.2 Isoprenoids: Functions and Applications .........................................................................38 3.3 Pathways of Isoprenoid Biosynthesis in Microalgae: Omics Advances ......................40