ABSTRACT
Hyperthermia is a state where cells absorb more heat than they can dissipate, which can be lethal to the cells. Such phenomenon has been found as a promising approach for cancer therapy, because it directly kills cancer cells and indirectly activates anticancer immunity [1]. Because focusing the heat on an intended region without damaging the healthy tissue was an important problem that arose by the treatment with hyperthermia, targeting of a specific region was important. If nanoparticles can target a specific malignant tissue, hyperthermia can be directed to this specific tissue. Unlike the conventional hyper thermic techniques, some studies showed that using nanoparticles for hyperthermia helped cancer cells to reach the lethal temperature without damaging the surrounding tissue [2].
