ABSTRACT
The design of a pharmaceutical dosage form has always taken into account the bioavailability of the therapeutic at the target site. Each dosage form is unique and reveals its intricacies related to the intended use. These variations in terms of formulations not only raise problems related to the limitations of the administration route but also to the specifi cities of each drug. The proper design of a formulation has to therefore take into account both considerations of the physicochemical and biological characteristics of the route of administration.
