ABSTRACT

ABSTRACT: Objective: Psychomotor retardation is present in 3% of population. Strabismus is associated 80%. This study is to determine the efficacy of Botulinum toxin in strabismus related to brain damage. Methods: Treatment was made with direct technique of Botulinum toxin considering age, strabismus type, number of injections, response and brain disease. Results: We analyze 30 patients 3.5 / 3 years old for 12.7 / 7.3 months. Eighty percent had moderate psychomotor retardation and 20% had a severe one. Good response: 44%, regular: 24%. Toxin applications: 1.7 / 1. Age and type of strabismus was not related to success of treatment (X2: 9.4, 7.8 to hypothesis). First application of toxin determined the response to treatment (Fisher test: 0.05). Moderate retardation was related to better response. Bad results was related to unstable brain disease. Conclusions: Because of bad prognosis to surgery in patients with brain damage, the use of Botulinum toxin must be considered as the first choice.