ABSTRACT
Figure 1 Overview of the physical mapping portion of the Candida albicans Genome Project. An example is shown of the assembly of a contig on chromosome 5. In the later stages of the map construction, probes are not sequenced. As more probes are tested, larger and larger contigs are constructed. The object is to develop complete contigs (overlapping sets of clones) for each chromosome. The ultimate goal, of course, is one contig per chromosome. This will allow the analysis of the location of repeated DNA and of the frequent chromosomal translocations. The finished map will facilitate the sequencing project by allowing the assignment of alleles with significant heterozygosity and locating any areas where sequence is unavailable.
