ABSTRACT

In the last two decades the use of human postmortem brain tissue in neurochemical and neuropharmacological research has received wide attention. Such studies have implicated serotonergic (Stanley & Mann, 1983; Arora & Meltzer, 1986), glutamatergic (Conley & Farber, 1995), dopaminergic (Crawley et al., 1986; Parade et al., 1990), GABAergic (Benes et al., 1996), cholinergic (Leonard et al., 1996), adrenergic (Mann et al., 1986; Meana et al., 1992; Arangoetal., 1993; Ordwayetal., 1994), and benzodiazepine (Kiuchi et al., 1989) receptors in the pathophysiology of mental disorders.