ABSTRACT

The use of capillary electrophoresis (CE) in various kinds of applications has increased rapidly, because it is suitable for compounds from small ions to macromolecules (up to ~7 MDa) [1-3]. CE has been used for separation, determination, and characterization of the compounds in food, environmental, clinical, and pharmaceutical matrices [2,4]. CE has not been such a popular

method in food analyses as it is in chemical, genetic, pharmaceutical, and clinical studies [5]. However, it is the only separation method that has gained positive attention and standardized in the determination of Creutzfeldt-Jacob disease (CJD) in bovines. For that reason, CE is also the only accepted method for the nal double checking of the status of the animal CJD [6].