ABSTRACT

The lowly mouse is highly regarded as a useful model for human diseases.  As  sequences  of  the  human  and  mouse  genomes  indicate  that  the  two  genomes are 85% identical, a multidisciplinary collaboration of basic and  clinical scientists worldwide has undertaken genomewide mutagenesis to  functionally annotate the mouse genome and develop new mouse models  relevant to human disease. In this chapter, Section 1 will present various  murine models of human diseases and relevant online resources, and Section 2 will demonstrate how to fetch some online murine model information from selected databases.