ABSTRACT

INTRODUCTION Supercritical fluid (SCF) technology experienced a significant boost over the past years. Apart from the classical use in extraction, preparative techniques like particle design or functionalization ofmaterial grewup. Today, these techniques can be applied underGMP conditions,making them available for use in drug formulation or food industry. One must, however, admit that some of these techniques actually are rather in an experimental state, but because of increasing speed of scientific development, they may become available in a short time. It seems, therefore, important to present these techniques within the actual standards of granulation.