ABSTRACT
Acne vulgaris is a common dermatological complaint, accounting for over 30%
of all visits to dermatologists. It is a multifactorial disease in which genetics and
hormonal changes play a role in its development. The clinical lesions of acne
develop from several steps, beginning with androgen stimulation of the seba-
ceous glands at or around puberty (1). This stimulates sebum production; the
constituents of sebum are comedogenic and contribute to early changes of the
follicle that lead to the microcomedo, the precursor lesion of acne vulgaris.
