ABSTRACT

The ability to acquire sequential, photographic, time-lapse images of the developing preimplantation human embryo in vitro has recently provided clinical embryologists with a powerful noninvasive embryo monitoring and selection tool. Time-lapse imaging was used to study fertilization and early human embryo kinetics more than 15 years ago, but this technology is now available for the routine clinical in vitro fertilization (IVF) setting [1]. The rst live birth after time-lapse imaging of embryos was reported by Pribenszky and colleagues in 2010, and since then time-lapse imaging of embryos has rapidly become a key topic and area of research in the eld of human fertility [2]. This chapter focuses on practical aspects of time-lapse imaging for embryo selection. It covers some of the key ndings that have been reported to date and considers the potential impact this exciting technology may have on our understanding of embryo development and on clinical IVF outcome.