ABSTRACT
JIE CHEN'•*, YOUNG CHANG NHO 2 and ALLAN S. HOFFMAN3 Department of Chemical Engineering and Technology, Shanghai University (Jiadiang Campus), Jiading, Shanghai 201800, China
2 Radiation Application Division, Korea Atomic Energy Research Institute, R O. Box 105, Yusong, Taejon, South Korea
Received 3 October 2003; accepted 7 January 2004
Abstract-Grafting of 2-methacryloyloxyethyl phosphorylcholine (MPC) and poly (ethylene glycol mathacrylate) (PEGMA) onto cellulose films was performed using the pre-irradiation grafting method. The effects of monomer concentration, solvent system and co-solvent composition, and reaction time on the degree of grafting were determined. The grafted samples were confirmed by FT-IR-ATR spectra. The blood compatibilities of the grafted cellulose were evaluated by platelet-rich plasma contact studies and viewed by scanning electron microscopy; non-grafted cellulose film sample was used as references. As a result, MPC and MPC/PEGMA were grafted on the surface of cellulose films. It was found that fewer platelets adhered to the MPC-grafted surfaces and that they showed less shape variation than the ungrafted references.
