ABSTRACT

Arsenic (As), commonly recognized as a toxic metalloid, is widely

distributed in nature,1 and its background concentration in soils

is generally less than 15 mg As kg−1.2 However, the distribution of As can vary depending on the release of naturally occurring

As through activities such as volcanism, hydrothermal activity, and

weathering of parent materials containing As-bearing minerals.

Anthropogenic activities, such as air emissions, soil amendments,

mining operations, and wood preservation, have also led to elevated

As levels.2,3 Chronic exposure to As has caused a wide variety

of adverse health effects including dermatological conditions and

various cancers.4 Recent studies also indicate that As is a potent

endocrine disruptor, potentially relevant to human developmental

problems and disease risk.5,6 Health problems associated with

exposure to As are a global issue, most notably in Southeast Asia. In

Bangladesh alone, it is estimated that more than 57 million people

rely on drinking water that contains As in excess of theWorld Health

Organization (WHO) standard.7