ABSTRACT
The interactions of some compounds such as anticancer drugs with
DNA have been performed by a variety of techniques. In recent
times electrochemical DNA biosensor systems have been taking an
increasing interest in the analysis of compound-DNA interactions for
understanding the action mechanism of many chemical molecules
due to their high sensitivity, portability, low-cost structure, single-
use property, and compatibility with microfabrication technology.
Based on these electrochemical methods, binding of compounds
onto DNA and/or general DNA damage occurred by these com-
pounds, have been identified by using the voltammetric signals
of guanine, adenine, or related compound molecules. In most of
these applications for the detection of compound-DNA interactions,
anticancer drugs have been studied because of their known effects
on DNA molecule.
