ABSTRACT
Biotechnology is in great need of low-cost intelligent biochips
capable of massive parallel detection to be used in portable
instrumentation. One way this may be achieved is by exploiting
mature semiconductor technologies for the development of biosen-
sor arrays. We review here two highly promising techniques for
label-free electrical detection of DNA hybridization: potentiometric
detection and electrochemical impedance spectroscopy. Field-effect
transistor technologies can play an important role in the develop-
ment of these techniques in biosensor microarrays.
