ABSTRACT

MC lysate (Kinoshita et al., 2005), suggesting a role for MC tryptase in the accumulation of MCs or other inflammatory cells in human atherosclerotic plaques.

Figure 5.1 Mast cells in human coronary atherosclerotic lesions. Anti-human tryptase antibody immunostaining detected mast cells in the shoulder area (panels A and B) and in the adventitia (panels C and D). Framed areas in panels A and C are shown at higher magnifications in panels B and D, respectively. Lumen, lipid core, and adventitia are indicated. V: microvessel.