ABSTRACT

In a broad sense, nanodevices are the critical enablers that will

allow exploiting the ultimate technological capabilities of chemical,

pharmaceutical, and biological systems. In this scenario, surface-

enhanced Raman scattering (SERS) spectroscopy is one of the

most promising analytical techniques for identification of molecular

species, able to detect several kinds of sample under different

environmental conditions and a good potential with respect to

low-concentration analytes. We illustrate here the possible uses

of a surface-enhanced microneedle-shaped fiber optics acting as

a multipurpose nanosensor. The optical probe takes advantage

from SERS to improve its sensibility. It adopts an active substrate

obtained by immobilization of nanoparticles on the manufactured

fiber substrate. The multipurpose nanosensing capabilities of the

optical probe will be highlighted by illustrating selected examples.