ABSTRACT

The concept of using external magnetic fields to achieve a pulsatile

release from polymer composites was first pursued by Langer and

coworkers in 1981 [1]. They incorporated magnetic steel beads in

ethylene vinyl acetate polymers and showed that the application

of low-frequency oscillating magnetic fields can be used to control

release rates of different compounds like bovine serum albumin

and insulin. In recent years, stimuli-responsive polymers, which

can respond to external stimuli, such as pH, temperature, light,

ultrasound, and the presence of magnetic or electric fields, have

attracted a great deal of interest [2-4].