ABSTRACT

This book examines stealth liposomes from a multidisciplinary approach, which includes theoretical polymer physics, organic synthesis, colloid science, and biology. Discussions include theory, chemistry, biochemistry, pharmacology, preclinical studies in model systems, and medical applications in humans.

chapter 5|16 pages

Physical Properties of Polymer-Grafted Bilayers

ByK. Hristova, D. Needham

chapter 7|10 pages

Measurement of the Range and Magnitude of the Repulsive Pressure between PEG-Coated Liposomes

ByT.J. Mclntosh, A.K. Kenworthy and D. Needham

chapter 8|20 pages

Modulation and Modeling of Interaction Forces between Lipid Bilayers Exposing Terminally Grafted Poolymer Chains

ByT.L. Kohl, D.E. Leckband, D.D. Lasic, and J.N. Israelachvili

chapter 9|10 pages

Polyethylene Glycol-Lipid Conjugates

ByS. Zalipsky

chapter 10|16 pages

Biological Properties of Sterically Stabilized Liposomes

ByM.C. Woodle, M.S. Newman, and P.K. Working

chapter 11|16 pages

Mechanism of Stealth® Liposomes Accumulation in Some Pathological Tissues

ByS.K. Huang, F.J. Martin, D.S. Friend, and D. Papahadjopoulos

chapter 14|24 pages

Tissue Uptake and Therapeutic Effects of Stealth® Doxorubicin

ByJ. Vaage, E. Barbera

chapter 17|14 pages

Stealth® Liposomes as Carriers of Antibiotics in Infectious Diseases

ByI. Bakker-Woudenberg, G. Storm, and M.C. Woodle

chapter 18|8 pages

Sterically Stabilized Liposome-Encapsulated Hemoglobin

ByS. Zheng, Y. Zheng, R. Beissinger

chapter 19|14 pages

PEG-Modified Liposomes for Gamma- and Magnetic Resonance Imaging

ByV.P. Torchilin, J. Narula, B.A. Khaw and V.S. Trubetskoy

chapter 20|12 pages

Antibody-Targeted Stealth® Liposomes

ByT.M. Alien, C.B. Hansen and S. Zalipsky